Movement Disorders (revue)

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Segmental ballistic movement overflow myoclonus: A clinical, electromyographic, and pharmacologic evaluation

Identifieur interne : 006125 ( Main/Exploration ); précédent : 006124; suivant : 006126

Segmental ballistic movement overflow myoclonus: A clinical, electromyographic, and pharmacologic evaluation

Auteurs : J. Stübgen [Afrique du Sud] ; Lotz [Afrique du Sud]

Source :

RBID : ISTEX:FD82B6B0535553A995DE84CEDF512FDC6E98A34F

Descripteurs français

English descriptors

Abstract

A 27‐year‐old man presented with a sporadic, nonprogressive, right‐sided, segmental movement disorder that had started at the age of 2 years. Ballistic movement overflow myoclonus was diagnosed clinically and by surface electromyography. Special investigations did not detect anything except atrophy of the left temporal lobe on CT scan. The movement intensity was attenuated by alcohol but was minimally affected by high doses of oral propranolol (320 mg daily), clonazepam (36 mg daily), or trihexyphenidyl (32 mg daily). High‐dose intravenous biperidine (10 mg) resulted in dramatic improvement, but with unacceptable side effects. The possible role of a cholinergic disturbance in generating myoclonus is discussed.

Url:
DOI: 10.1002/mds.870060415


Affiliations:


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Le document en format XML

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<term>Central nervous system</term>
<term>Cholinergic Fibers (drug effects)</term>
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<term>Muscle Contraction (drug effects)</term>
<term>Muscle Contraction (physiology)</term>
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<term>Myoclonus (drug therapy)</term>
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